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Search Results for " capsid protein "

15

Compounds

Cat No. Product Name Synonyms Targets
T16500 PF-3450074 PF-74 HIV Protease
PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nu...
T9054 RO6889678 HBV
RO6889678 is HBV inhibitor with a complex ADME profile.
T3345 Hederasaponin B Eleutheroside M,Hederacoside B Others , Virus Protease
Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.
T5782 Bevirimat YK FH312,MPC-4326,PA-457 HIV Protease
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.
TP1739L HEX3 acetate(688805-40-5 free base) Others
HEX3 acetate is a fragment of the adenoviral hexon. Hexon is the major capsid protein of adenovirion and is comprised of three identical polypeptide chains.
T28860 ST-148 ST148
ST-148 is a potent inhibitor for Dengue virus capsid. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity.
T10446 BA-53038B Others
BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).
TP1739 HEX3
HEX3 is a truncated form of the adenoviral hexon, which serves as the primary capsid protein for adenovirions. It consists of three identical polypeptide chains.
T61462 EV-A71-IN-1
EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 μM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP...
T61558 HBV-IN-21
HBV-IN-21 (Compound II-8b) is a potent inhibitor of HBV DNA replication, exhibiting an IC50 of 2.2 μM. It demonstrates a favorable binding affinity (K D = 60.0 μM) for the HBV 4 capsid protein, thereby enabling effective...
T74211 HIV-1 inhibitor-12
HIV-1 inhibitor-12 is a potent inhibitor that targets the HIV-1 capsid protein, effectively preventing its polymerization with an inhibition concentration (IC 50) of 9 nM.
T73492 AB-836
AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.
T78300 Anivovetmab KIND-030
Anivovetmab (KIND-030), an IgG2 type monoclonal antibody targeting the VP2 protein (parvovirus major capsid), offers a potential research avenue for canine parvovirus infection.
T73500 AB-506
AB-506 is a compound that serves as an orally administered inhibitor specifically targeting the hepatitis B virus (HBV) core protein to obstruct HBV replication. It achieves this by binding to the HBV core protein, accel...
T83704 A20FMDV2 TFA
A20FMDV2, a peptide derived from the α-helical RGD cell-interacting domain of the VP1 capsid protein of foot-and-mouth disease virus (FMDV) serotype O, targets and binds αVβ6 integrin. It effectively disrupts αVβ6 integr...
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